12 (S) -Hydroxy-16-heptadecynoic acid
12 (S) -Hydroxy-16-heptadecynoic acid ((12S) -12-Hydroxy-15-hexadecynoic acid) is a mechanism-based inhibitor of cytochrome P450 ω-hydroxylase. It inhibits prostaglandin ω-hydroxylase with a Ki value of 1.8 μM.
Product Specifications
CAS Number
148019-74-3
Product Name Alternative
(12S) -12-Hydroxy-15-hexadecynoic acid
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/12-s-hydroxy-16-heptadecynoic-acid.html
Smiles
C#CCCC[C@@H](O)CCCCCCCCCCC(O)=O
Molecular Formula
C17H30O3
Molecular Weight
282.42
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Burger, et al. Mechanism-based inhibitors of prostaglandin w -hydrolase: (R) - and (S) -12-hydroxy-16-heptadecynoic acid and 2,2-dimethyl-12-hydroxy-16-heptadecynoic acid. J. Med. Chem. 36, 1418-1424 (1993) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940050-100 1x 100 µL
IgA Secretory Component (SC05), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880266-500 1x 500 µL
Human IgG Immunoglobulin (IG266), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC881231-500 1x 500 µL
Eosinophil Peroxidase (AHE-1), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740633-500 1x 500 µL
Von Willebrand Factor (3E2D10), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680845-500 1x 500 µL
Mucin 1 / EMA / Episialin / CD227 (MUC1/845), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details