Human Factor Va

<strong>Human Factor Va</strong>_x000D_ <strong>Catalog number:</strong> B2016625_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 25 µg _x000D_ <strong>Molecular Weight or Concentration:</strong> 168000_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> Human Factor Va_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong> _x000D_ 1: Foster WB, Tucker MM, Katzmann JA, Miller RS, Nesheim ME, Mann KG. Monoclonal antibodies to human coagulation factor V and factor Va Blood. 1983 Jun;61(6):1060-7._x000D_ 2: Maruyama I, Salem HH, Majerus PW. Coagulation factor Va binds to human umbilical vein endothelial cells and accelerates protein C activation J Clin Invest. 1984 Jul;74(1):224-30. _x000D_ 3: Hockin MF, Kalafatis M, Shatos M, Mann KG. Protein C activation and factor_Va inactivation on human umbilical vein endothelial cells Arterioscler Thromb Vasc Biol. 1997 Nov;17(11):2765-75. _x000D_ 4: Krishnaswamy S, Church WR, Nesheim ME, Mann KG. Activation of human prothrombin by human prothrombinase. Influence of factor_Va on the reaction mechanism J Biol Chem. 1987 Mar 5;262(7):3291-9._x000D_ 5: Schreuder M, Reitsma PH, Bos MHA. Blood coagulation factor_Va's key interactive residues and regions for prothrombinase assembly and prothrombin binding J Thromb Haemost. 2019 Aug;17(8):1229-1239. _x000D_ 6: Friedmann AP, Koutychenko A, Wu C, Fredenburgh JC, Weitz JI, Gross PL, Xu P, Ni F, Kim PY. Identification and characterization of a factor Va-binding site on human prothrombin fragment 2 Sci Rep. 2019 Feb 21;9(1):2436. _x000D_ 7: Rosing J, Tans G. Factor V Int J Biochem Cell Biol. 1997 Oct;29(10):1123-6. _x000D_ 8: Rosing J, Bakker HM, Thomassen MC, Hemker HC, Tans G. Characterization of two forms of human factor Va with different cofactor activities J Biol Chem. 1993 Oct 5;268(28):21130-6._x000D_ 9: Kalafatis M, Rand MD, Mann KG. The mechanism of inactivation of human factor_V and human_factor_Va by activated protein C J Biol Chem. 1994 Dec 16;269(50):31869-80._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/8427963">10: Kalafatis M, Rand MD, Jenny RJ, Ehrlich YH, Mann KG. Phosphorylation of factor_Va and factor VIIIa by activated platelets Blood. 1993 Feb 1;81(3):704-19.</a>_x000D_ <br><strong>Products Related to Human Factor Va can be found at</strong> <a href="https://moleculardepot.com/product-category/Enzymes/"> Enzymes</a>