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LY-395153

LY-395153 is an AMPA receptor enhancer with the activity of binding to AMPA receptors. LY-395153 can bind to natural and recombinant AMPA receptors, and its binding is affected by AMPA receptor agonists and can be competitively or non-competitively inhibited by some compounds. It is a useful probe for marking unique regulatory sites of AMPA receptors.

Product Specifications

CAS Number

211313-51-8

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ly-395153.html

Smiles

O=C(C1=CC=CC=C1)NC2=CC=C(C(CNS(=O)(C(C)C)=O)C)C=C2

Molecular Formula

C19H24N2O3S

Molecular Weight

360.47

References & Citations

[1]Binding of an AMPA receptor potentiator ([3H]LY395153) to native and recombinant AMPA receptors

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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