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Ferroptosis-IN-11

Ferroptosis-IN-11 (compound 43) is a ferroptosis inhibitor. Ferroptosis-IN-11 can inhibit Erastin induced ferroptosis in HT-1080 human fibroblasts (EC50=36 nM). Ferroptosis-IN-11 can be used in the study of cardiovascular disease and neurodegeneration[1].

Product Specifications

CAS Number

1266755-01-4

UNSPSC

12352005

Target

Ferroptosis

Type

Reference compound

Related Pathways

Apoptosis

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ferroptosis-in-11.html

Smiles

FC1=C(F)C=C(NCC(C2=CC=CC=C2)N3)C3=C1

Molecular Formula

C14H12F2N2

Molecular Weight

246.26

References & Citations

[1]HongXu Lei, et al. "A quantum-chemical approach to develop tetrahydroquinoxaline as potent ferroptosis inhibitors." Journal of Molecular Structure 1228 (2021) : 129485.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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