Ferroptosis-IN-11
Ferroptosis-IN-11 (compound 43) is a ferroptosis inhibitor. Ferroptosis-IN-11 can inhibit Erastin induced ferroptosis in HT-1080 human fibroblasts (EC50=36 nM). Ferroptosis-IN-11 can be used in the study of cardiovascular disease and neurodegeneration[1].
Product Specifications
CAS Number
1266755-01-4
UNSPSC
12352005
Target
Ferroptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ferroptosis-in-11.html
Smiles
FC1=C(F)C=C(NCC(C2=CC=CC=C2)N3)C3=C1
Molecular Formula
C14H12F2N2
Molecular Weight
246.26
References & Citations
[1]HongXu Lei, et al. "A quantum-chemical approach to develop tetrahydroquinoxaline as potent ferroptosis inhibitors." Journal of Molecular Structure 1228 (2021) : 129485.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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