5-trans-PGE2 (Standard)
Product Specifications
UNSPSC Description
5-trans-PGE2 (Standard) is the analytical standard of 5-trans-PGE2. This product is intended for research and analytical applications. 5-trans-PGE2 (5-trans Prostaglandin E2) is the active isomer of PGE2 and a potent activator of aromatase. Supplements the process of paracrine signaling between epithelial cells (expressing high levels of PGE2) and surrounding stromal cells (expressing high levels of aromatase). This process is involved in the growth and development of breast cancer[1].
Target Antigen
Cytochrome P450; Prostaglandin Receptor
Type
Reference Standards
Related Pathways
GPCR/G Protein;Metabolic Enzyme/Protease
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/5-trans-pge2-standard.html
Smiles
CCCCC[C@H](O)/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)C/C=C/CCCC(O)=O
Molecular Weight
352.47
References & Citations
[1]Richards JA, et al. Prostaglandin E2 regulates aromatase activity and expression in human adipose stromal cells via two distinct receptor subtypes. J Clin Endocrinol Metab. 2003 Jun;88(6):2810-6.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-135023R/5-trans-PGE2-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-135023R/
CAS Number
36150-00-2
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