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Anti-Mouse/Human PrP/prion protein Antibody (TW1)

Anti-Mouse/Human PrP/prion protein Antibody (TW1) is a mouse-derived IgG2a type antibody inhibitor, targeting to mouse/human PrP/prion protein. Anti-Mouse/Human PrP/prion protein Antibody (TW1) binds to both PrPc (cellular prion protein) and PrPSc (Scrapie Prion Protein) and blocks the interaction of prion protein with tau protein. Anti-Mouse/Human PrP/prion protein Antibody (TW1) can be used for the researches of Alzheimer’s disease (AD) [1].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

Prion Protein; Tau Protein

Type

Inhibitory Antibodies

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/anti-mouse-human-prp-prion-protein-antibody-tw1.html

Solubility

10 mM in DMSO

Smiles

[Anti-Mouse/HumanPrP/prionproteinAntibody(TW1)]

Molecular Weight

(150 kDa)

References & Citations

[1]Boutajangout A, et al. Passive Immunization With a Novel Monoclonal Anti-PrP Antibody TW1 in an Alzheimer's Mouse Model With Tau Pathology. Front Aging Neurosci. 2021 Feb 25;13:640677.

Shipping Conditions

Room temperature

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Frequently Asked Questions

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