UBE2T/FANCL-IN-1
Product Specifications
UNSPSC Description
UBE2T/FANCL-IN-1 is a potent inhibitor of UBE2T/FANCL-mediated FANCD2 monoubiquitylation that sensitizes cells to the DNA cross-linking agent, Carboplatin[1].
Target Antigen
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ube2t-fancl-in-1.html
Purity
99.83
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
CC(CCCC1)N1CC2=NN3C(N4CCN(CC)CC4)=CC(C)=NC3=N2
Molecular Weight
357.50
References & Citations
[1]Cornwell MJ, et al. Small-Molecule Inhibition of UBE2T/FANCL-Mediated Ubiquitylation in the Fanconi Anemia Pathway. ACS Chem Biol. 2019;14(10):2148-2154.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-126539/UBE2T-FANCL-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-126539/UBE2T-FANCL-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1359415-02-3
Available Sizes
Curated Selection
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