15-epi Prostaglandin A1
15-epi Prostaglandin A1 (15-epi PGA1) is the 15 (R) stereoisomer of PGA1. PGA1 causes renal vasodilation, increased urine sodium excretion, and decreased arterial pressure in hypertensive models[1][2].
Product Specifications
CAS Number
20897-92-1
Product Name Alternative
15-epi PGA1
UNSPSC
12352211
Hazard Statement
H225-H319-H336
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/15-epi-prostaglandin-a1.html
Smiles
CCCCC[C@H](/C=C/[C@@H](C=CC1=O)[C@H]1CCCCCCC(O)=O)O
Molecular Formula
C20H32O4
Molecular Weight
336.47
Precautions
P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501
References & Citations
[1]Murakami A, et al. Conformational analysis of prastaglandins. III. Study on active sites and conformation-action relationship. Chem Pharm Bull (Tokyo) . 1977 Dec;25 (12) :3155-62.|[2]Krakoff LR, et al. Differential effect of prostaglandin A1 in hypertensive patients with low, normal and high renin. Clin Sci Mol Med Suppl. 1975 Jun;2:311s-313s.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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