Arbaprostil

Arbaprostil is an orally active PGE1 (HY-B0131) analog. Arbaprostil protects the gastrointestinal mucosa from stomach acid and other irritants, promotes healing rate of gastric ucler through the antisecretory effect[1][2].

Product Specifications

CAS Number

[55028-70-1]

UNSPSC

12352211

Hazard Statement

H302-H360

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/arbaprostil.html

Solubility

10 mM in DMSO

Smiles

CCCCC[C@@](O)(/C=C/[C@H]1[C@@H](CC([C@@H]1C/C=C\CCCC(O)=O)=O)O)C

Molecular Formula

C21H34O5

Molecular Weight

366.49

Precautions

P264-P270-P280-P330-P405-P501

References & Citations

[1]Li JY, Nagata T, Yoshida M, Yagi N, Katoh K, Haramoto T, Itoh K, Iwasaki A, Matsuo Y. Effect of 15 (R) -15-methyl PGE2 (arbaprostil) on duodenal bicarbonate secretion in rat. Gastroenterol Jpn. 1989 Feb;24 (1) :8-11.|[2]Okabe S, et al., Effects of 15 (R) -15-methyl prostaglandin E2 (arbaprostil) on gastric secretion and various gastric lesions induced in rats. Jpn J Pharmacol. 1986 Feb;40 (2) :329-37.