Arbaprostil
Arbaprostil is an orally active PGE1 analog. Arbaprostil protects the gastrointestinal mucosa from stomach acid and other irritants, promotes healing rate of gastric ucler through the antisecretory effect[1][2].
Product Specifications
CAS Number
55028-70-1
UNSPSC
12352211
Hazard Statement
H302-H360
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/arbaprostil.html
Solubility
10 mM in DMSO
Smiles
CCCCC[C@@](O)(/C=C/[C@H]1[C@@H](CC([C@@H]1C/C=C\CCCC(O)=O)=O)O)C
Molecular Formula
C21H34O5
Molecular Weight
366.49
Precautions
P264-P270-P280-P330-P405-P501
References & Citations
[1]Li JY, Nagata T, Yoshida M, Yagi N, Katoh K, Haramoto T, Itoh K, Iwasaki A, Matsuo Y. Effect of 15 (R) -15-methyl PGE2 (arbaprostil) on duodenal bicarbonate secretion in rat. Gastroenterol Jpn. 1989 Feb;24 (1) :8-11.|[2]Okabe S, et al., Effects of 15 (R) -15-methyl prostaglandin E2 (arbaprostil) on gastric secretion and various gastric lesions induced in rats. Jpn J Pharmacol. 1986 Feb;40 (2) :329-37.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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