Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Tryptanthrin (Standard)

Tryptanthrin (Standard) is the analytical standard of Tryptanthrin. This product is intended for research and analytical applications. Tryptanthrin is an indole quinazoline that could be an alkaloid from indigo-bearing plants. Tryptanthrin is a potent and orally active cellular Leukotriene (LT) biosynthesis inhibitor. Tryptanthrin has anticancer activity. Tryptanthrin suppresses the expression levels of NOS1, COX-2, and NF-κB and regulates the expression levels of IL-2, IL-10, and TNF-α[1][2].

Product Specifications

CAS Number

[13220-57-0]

UNSPSC

12352005

Target

COX; Interleukin Related; Leukotriene Receptor; NF-κB; NO Synthase; Reference Standards; TNF Receptor

Type

Reference Standards

Related Pathways

Apoptosis; GPCR/G Protein; Immunology/Inflammation; NF-κB; Others

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tryptanthrin-standard.html

Purity

98.77

Smiles

O=C1C2=CC=CC=C2N3C(C4=CC=CC=C4N=C13)=O

Molecular Formula

C15H8N2O2

Molecular Weight

248.24

References & Citations

[1]Zeng Q, et, al. Tryptanthrin exerts anti-breast cancer effects both in vitro and in vivo through modulating the inflammatory tumor microenvironment. Acta Pharm. 2021 Jun 1;71 (2) :245-266.|[2]Pergola C, et, al. On the inhibition of 5-lipoxygenase product formation by tryptanthrin: mechanistic studies and efficacy in vivo. Br J Pharmacol. 2012 Feb;165 (3) :765-76.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, sealed storage, away from light and moisture

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N6607R/Tryptanthrin-Standard-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N6607R/Tryptanthrin-Standard-SDS-MedChemExpress.pdf

Scientific Category

Reference Standards

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

CCDC60 293 Cell Lysate
403753 0.1 mg

CCDC60 293 Cell Lysate

Ask
View Details
MPP10 rabbit pAb
ES3809-01 50 µL

MPP10 rabbit pAb

Ask
View Details
MPP10 rabbit pAb
ES3809-02 100 µL

MPP10 rabbit pAb

Ask
View Details
FITC-Linked Anti-Complement 1 Inhibitor (C1INH)
FY-AB44019-01 1 mL

FITC-Linked Anti-Complement 1 Inhibitor (C1INH)

Ask
View Details
FITC-Linked Anti-Complement 1 Inhibitor (C1INH)
FY-AB44019-02 100 µL

FITC-Linked Anti-Complement 1 Inhibitor (C1INH)

Ask
View Details
FITC-Linked Anti-Complement 1 Inhibitor (C1INH)
FY-AB44019-03 200 µL

FITC-Linked Anti-Complement 1 Inhibitor (C1INH)

Ask
View Details