Antiproliferative agent-62
Antiproliferative agent-62 (compound 5) is a functionalized benzylidene-indolin-2-one with notable antiproliferative activity and NQO1 activity induciton funciton, particularly in inducing NQO1 expression in murine Hepa1c1c7 cells and demonstrating effectiveness against human cancer cell lines, including MCF-7 and HCT116.
Product Specifications
CAS Number
856435-40-0
UNSPSC
12352005
Target
Quinone Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antiproliferative-agent-62.html
Smiles
O=C1NC2=CC=CC=C2/C1=C\C3=C(C=C(C=C3)OC)OC
Molecular Formula
C17H15NO3
Molecular Weight
281.31
References & Citations
[1]Functionalized 3-benzylidene-indolin-2-ones: inducers of NAD (P) H-quinone oxidoreductase 1 (NQO1) with antiproliferative activity
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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