Hexanorcucurbitacin D
Hexanorcucurbitacin D, a cucurbitacin, is a weak ecdysteroid receptor agonist. Hexanorcucurbitacin D can be isolated from Trichosanthes cucumeroides roots. Hexanorcucurbitacin D can be used for the research of cardiovascular disease (CVD) [1][2].
Product Specifications
CAS Number
29065-05-2
UNSPSC
12352211
Target
FXR
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/hexanorcucurbitacin-d.html
Solubility
10 mM in DMSO
Smiles
CC([C@H]1[C@@H](C[C@]2([C@@H]3CC=C4[C@H]([C@@]3(C(C[C@]12C)=O)C)C[C@@H](C(C4(C)C)=O)O)C)O)=O
Molecular Formula
C24H34O5
Molecular Weight
402.52
References & Citations
[1]Xianjing Zhang, et al. Lipid-Lowering Activities of Cucurbitacins Isolated from Trichosanthes cucumeroides and Their Synthetic Derivatives. J Nat Prod. 2020 Dec 24;83 (12) :3536-3544.|[2]L Dinan, et al. Cucurbitacins are insect steroid hormone antagonists acting at the ecdysteroid receptor. Biochem J. 1997 Nov 1;327 (Pt 3) (Pt 3) :643-50.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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