Pomalidomide 4'-PEG5-acid

Pomalidomide 4'-PEG5-acid (Pomalidomide-PEG5-CO2H) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 5-unit PEG linker used in PROTAC technology[1].

Product Specifications

CAS Number

[2139348-63-1]

Product Name Alternative

Pomalidomide-PEG5-CO2H

UNSPSC

12352005

Hazard Statement

H361

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pomalidomide-4-peg5-acid.html

Purity

97.0

Solubility

DMSO : 200 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(O)CCOCCOCCOCCOCCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O

Molecular Formula

C26H35N3O11

Molecular Weight

565.57

Precautions

H361

References & Citations

[1][1]Jing Liu, et al. Cyclic-amp response element binding protein (cbp) and/or adenoviral e1a binding protein of 300 kda (p300) degradation compounds and methods of use. WO2020173440A1.