Anisodine (hydrobromide)
Product Specifications
UNSPSC Description
Anisodine hydrobromide is a neuroprotective compound that interacts with muscarinic receptors (M1-M5) in cerebral ischemic diseases. Anisodine hydrobromide effectively reduces exacerbated M1, M2, M4, and M5 receptor expression in brain tissues under hypoxia/reoxygenation conditions. Anisodine hydrobromide demonstrates concentration-dependent inhibition of calcium ion influx and reactive oxygen species (ROS) levels, elucidating its neuroprotective mechanisms. Anisodine hydrobromide leads to decreased aspartate levels in HM cells during hypoxia, highlighting its effects on neurotransmitter modulation. Anisodine hydrobromide holds promising clinical prospects as a potential therapeutic agent for ischemic brain diseases, warranting further investigation into its mechanisms of action.
Target Antigen
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/anisodine-hydrobromide.html
Smiles
CN1[C@@H](C[C@H](OC([C@@](O)(CO)C2=CC=CC=C2)=O)C[C@H]31)[C@H]4[C@@H]3O4.Br
Molecular Weight
400.26
References & Citations
[1]Modulation of muscarinic receptors by anisodine hydrobromide in cerebral ischemia
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-127022A/Anisodine-hydrobromide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-127022A/
Clinical Information
Phase 3
CAS Number
76822-34-9
Curated Selection
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