2-Thiobarbituric acid

2-Thiobarbituric acid is a commonly used colorimetric reagent for the detection of malondialdehyde (MDA), a marker of lipid peroxidation. 2-Thiobarbituric acid forms a complex with MDA that can be quantified by colorimetric detection at 532 nm as a measure of lipid peroxidation[1].

Product Specifications

CAS Number

[504-17-6]

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2-thiobarbituric-acid.html

Purity

99.76

Smiles

S=C(NC(C1)=O)NC1=O

Molecular Formula

C4H4N2O2S

Molecular Weight

144.15

Precautions

H302, H315, H319, H335

References & Citations

[1]Knight J A, et al. Specificity of the thiobarbituric acid reaction: its use in studies of lipid peroxidation[J]. Clinical chemistry, 1988, 34 (12) : 2433-2438.|[2]Güner O Z, et al. 2-Thiobarbituric acid addition improves structural integrity and controlled drug delivery of biocompatible pectin hydrogels. International Journal of Polymeric Materials and Polymeric Biomaterials, 2021, 70 (10) : 703-711.