Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

(E/Z) -Zotiraciclib (citrate)

(E/Z) -Zotiraciclib citrate is a potent CDK2, JAK2, and FLT3 inhibitor[1].

Product Specifications

CAS Number

[1204918-73-9]

Product Name Alternative

(E/Z) -TG02 (citrate) ; (E/Z) -SB1317 (citrate)

UNSPSC

12352005

Target

CDK; FLT3; JAK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/e-z-zotiraciclib-citrate.html

Purity

99.83

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

OC(C(O)=O)(CC(O)=O)CC(O)=O.CN1CC2=CC(NC3=NC(C4=CC(OCC/C=C/C1)=CC=C4)=CC=N3)=CC=C2

Molecular Formula

C29H32N4O8

Molecular Weight

564.59

References & Citations

[1]William AD, et al. Discovery of kinase spectrum selective macrocycle (16E) -14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo[19.3.1.1 (2,6) .1 (8,12) ]heptacosa-1 (25),2 (26),3,5,8 (27),9,11,16,21,23-decaene (SB1317/TG02), a potent inhibitor of cyclin dependent kinases (CDKs), Janus kinase 2 (JAK2), and fms-like tyrosine kinase-3 (FLT3) for the treatment of cancer. J Med Chem. 2012;55 (1) :169-196.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CDK2; JAK2

Available Sizes

More Discoveries

Explore Other Products

Browse additional items from our catalog

Trim2 siRNA Oligos set (Mouse)
47753174 3x 5 nmol

Trim2 siRNA Oligos set (Mouse)

Sign In for Pricing
View Details
Recombinant Borrelia Garinii rplW Protein (aa 1-98)
VAng-Lsx2089-1mgEcoli 1 mg (E. coli)

Recombinant Borrelia Garinii rplW Protein (aa 1-98)

Sign In for Pricing
View Details
Recombinant Staphylococcus epidermidis Heme A synthase (ctaA), partial
MBS7093022 Inquire

Recombinant Staphylococcus epidermidis Heme A synthase (ctaA), partial

Sign In for Pricing
View Details
Ift81 ORF Vector (Mouse) (pORF)
ORF047717 1.0 µg DNA

Ift81 ORF Vector (Mouse) (pORF)

Sign In for Pricing
View Details
Slc6a9 (NM_008135) Mouse Tagged ORF Clone
MG209620 10 µg

Slc6a9 (NM_008135) Mouse Tagged ORF Clone

Sign In for Pricing
View Details
Ist1 3'UTR GFP Stable Cell Line
TU256403 1.0 mL

Ist1 3'UTR GFP Stable Cell Line

Sign In for Pricing
View Details