Canthin-6-one

Canthin-6-one is an indole alkaloid, displays antibacterial and anti-inflammatory activities[1][2].

Product Specifications

CAS Number

[479-43-6]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Akt; Bacterial; COX; NF-κB; NO Synthase

Type

Natural Products

Related Pathways

Anti-infection; Immunology/Inflammation; NF-κB; PI3K/Akt/mTOR

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/canthin-6-one.html

Purity

99.92

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C1N2C3=C(N=CC=C3C4=C2C=CC=C4)C=C1

Molecular Formula

C14H8N2O

Molecular Weight

220.23

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]O'Donnell G, Gibbons S. Antibacterial activity of two canthin-6-one alkaloids from Allium neapolitanum. Phytother Res. 2007;21 (7) :653-657. |[2]Cho SK, et al., Anti-inflammatory Effects of Canthin-6-one Alkaloids from Ailanthus altissima. Planta Med. 2018 May;84 (8) :527-535.