Cabozantinib L-Malate Salt

Product Specifications

CAS Number

9007-83-4

Synonyms

Butanedioic acid, 2-hydroxy-, (2S)-, compd. with N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1); Cabozantinib S-malate; Cabozantinib s-malate; Cometriq; XL 184; Cabozantinib L-malate salt; Cabozantinib (S)-malate

Hazard Statement

Harmful if swallowed

Purity

>95% (HPLC)

Smiles

COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc5ccc(F)cc5)cc3)c2cc1OC.O[C@@H](CC(=O)O)C(=O)O

Molecular Formula

C28 H24 F N3 O5 . C4 H6 O5

Molecular Weight

635.59

InChI

InChI=1S/C28H24FN3O5.C4H6O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18;5-2(4(8)9)1-3(6)7/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34);2,5H,1H2,(H,6,7)(H,8,9)/t;2-/m.0/s1

Additionnal Information

IUPAC name: 1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;(2S)-2-hydroxybutanedioic acid

Shipping Conditions

Room Temperature

Storage Conditions

+4°C