Cepharadione B
Cepharadione B (compound 22) is a natural compound isolated from the leaves of Piper sanctum. Cepharadione B is a tyrosinase inhibitor with an IC50 value of 170 μM, and inhibits cell growth in A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT-15 cells[1][2][3].
Product Specifications
CAS Number
55610-02-1
UNSPSC
12352005
Target
Endogenous Metabolite; Tyrosinase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cepharadione-b.html
Solubility
10 mM in DMSO
Smiles
O=C1C(N(C)C2=C3C1=CC(OC)=C(OC)C3=C4C(C=CC=C4)=C2)=O
Molecular Formula
C19H15NO4
Molecular Weight
321.33
References & Citations
[1]Mata R, et al. Antimycobacterial compounds from Piper sanctum. J Nat Prod. 2004;67 (12) :1961-1968.|[2]Kim SK, et al. Cytotoxic alkaloids from Houttuynia cordata. Arch Pharm Res. 2001;24 (6) :518-521.|[3]Chou SC, et al. The constituents and their bioactivities of Houttuynia cordata. Chem Pharm Bull (Tokyo) . 2009;57 (11) :1227-1230.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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