Actagardin

Actagardin is a tetracyclic lantibiotic produced by several species of Actinoplanes. It is composed of macrocyclic rings formed by thioether bridges. Actagardin preferably targets Gram-positive bacteria, inhibiting the synthesis of peptidoglycan.

Product Specifications

CAS Number

[59165-34-3]

Product Name Alternative

Antibiotic A 3802-IV-3; Gardimycin

UNSPSC

12352209

Target

Antibiotic

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/actagardin.html

Smiles

[CSGWVCCLCICGCVICAC(Carbasulfidebridge:Cys1-Cys6,Cys7-Cys12,Cys9-Cys17,Cys14-Cys19)]

Molecular Formula

C81H124N20O24S4

Molecular Weight

1890.23

References & Citations

[1]Brötz, et al. New insights into the mechanism of action of lantibiotics—diverse biological effects by binding to the same molecular target. J. Antimicrob. Chemother. 46 (1), 1-6 (2000) .