EGFR/HER2-IN-15
Product Specifications
UNSPSC Description
EGFR/HER2-IN-15, a dihydropyrimidine, is a potent EGFR/HER2 inhibitor. EGFR/HER2-IN-15 significantly inhibits EGFRwt activity with an IC50 of 37.21 nM. EGFR/HER2-IN-15 has anticaner effects[1].
Target Antigen
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-her2-in-15.html
Smiles
O=C1NC(C)=C(C(NC2=CC=C(OC)C=C2OC)=O)C(C3=CC(OC)=C(OCC4=CC=CC=C4)C=C3)N1
Molecular Weight
503.55
References & Citations
[1]Syed Faizanm, et al. Novel dihydropyrimidines as promising EGFR & HER2 inhibitors: Insights from experimental and computational studies. Eur J Med Chem. 2024 Jun 19:275:116607.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162623/EGFR-HER2-IN-15-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162623/
Clinical Information
No Development Reported
Curated Selection
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