EGFR/HER2-IN-15
EGFR/HER2-IN-15, a dihydropyrimidine, is a potent EGFR/HER2 inhibitor. EGFR/HER2-IN-15 significantly inhibits EGFRwt activity with an IC50 of 37.21 nM. EGFR/HER2-IN-15 has anticaner effects[1].
Product Specifications
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-her2-in-15.html
Smiles
O=C1NC(C)=C(C(NC2=CC=C(OC)C=C2OC)=O)C(C3=CC(OC)=C(OCC4=CC=CC=C4)C=C3)N1
Molecular Formula
C28H29N3O6
Molecular Weight
503.55
References & Citations
[1]Syed Faizanm, et al. Novel dihydropyrimidines as promising EGFR & HER2 inhibitors: Insights from experimental and computational studies. Eur J Med Chem. 2024 Jun 19:275:116607.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EGFR/ErbB1/HER1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15386928 1 Vial
Lentiviral human SYCE3 sgRNA gene knockout kit - Lentiviral human SYCE3 sgRNA gene knockout kit (25)
Ask
View Details 
GTR15298037 1 Vial
Lentiviral mouse Aqp11 shRNA (UAS) - Lentiviral mouse Aqp11 shRNA (UAS, iRFP) (25)
Ask
View Details 
MBS7172568 Inquire
Rabbit anti-Escherichia coli (strain SE11) DNAA Polyclonal Antibody
Ask
View Details 