SIRT2-IN-16

SIRT2-IN-16 (compund 17) is a prostate-specific membrane antigen (PSMA) -targeted SIRT2 inhibitor[1].

Product Specifications

UNSPSC

12352211

Target

Sirtuin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(O)CC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCCCNC(CCC1=CN(CCOCCOCCOCCOCCNC([C@@H](NC(OCC2=CC=CC=C2)=O)CCCCNC(CCCCCCCCCCCCC)=S)=O)N=N1)=O)=O

Molecular Formula

C55H91N9O15S

Molecular Weight

1150.43

References & Citations

[1]Yu J, et al. Design, synthesis and biological evaluation of prostate-specific membrane antigen (PSMA) -targeted SIRT2 inhibitors. Bioorg Chem. 2024 Dec;153:107784.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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