Neoantimycin
Neoantimycin is a GRP78/BiP and K-Ras regulator with anticancer activity. Its biosynthesis is catalyzed by a hybrid nonribosomal peptide synthetase/polyketide synthase (NRPS/PKS) system[1].
Product Specifications
CAS Number
22862-63-1
UNSPSC
12352005
Target
HSP; Ras
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; GPCR/G Protein; MAPK/ERK Pathway; Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/neoantimycin.html
Smiles
O=C(C1=C(C(NC=O)=CC=C1)O)N[C@@H]2C(O[C@H](C(O[C@@H]([C@@H](C(C)(C(O[C@@](C(O[C@@H]2C)=O)([H])[C@@H](C)CC)=O)C)O)CC3=CC=CC=C3)=O)C(C)C)=O
Molecular Formula
C36H46N2O12
Molecular Weight
698.76
References & Citations
[1]Skyrud W, et al. Biosynthesis of the 15-Membered Ring Depsipeptide Neoantimycin. ACS Chem Biol. 2018 May 18;13 (5) :1398-1406.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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