Chaetochromin A
Chaetochromin A (Compound 1) is a fungal metabolite. Chaetochromin A shows inhibitory effect on botulinum neurotoxin serotype A (BoNT A) (IC50= 24.6 μM) [1].
Product Specifications
CAS Number
[75514-37-3]
Product Name Alternative
Chaetochromin
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Endogenous Metabolite; Fungal
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/chaetochromin-a.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(O[C@@H]([C@H]1C)C)C=C3C(C4=C(C=C(C(C(O)=C56)=C4C=C6O[C@H](C)[C@@H](C)C5=O)O)O)=C(O)C=C(O)C3=C2O
Molecular Formula
C30H26O10
Molecular Weight
546.52
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Cardellina JH 2nd, et al. Fungal bis-Naphthopyrones as Inhibitors of Botulinum Neurotoxin Serotype A. ACS Med Chem Lett. 2012 Apr 2;3 (5) :387-91.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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