(Z) -Iloprost

(Z) -Iloprost ((Z) -Ciloprost; (Z) -ZK 36374) is a vasodilator that prevents heparin-induced platelet activation[1][2][3].

Product Specifications

CAS Number

[82889-99-4]

Product Name Alternative

(Z) -Ciloprost; (Z) -ZK 36374

UNSPSC

12352211

Hazard Statement

H225-H319-H336-H361

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/z-iloprost.html

Solubility

10 mM in DMSO

Smiles

CC#CCC(C)[C@H](O)/C=C/[C@@H]1[C@]2([H])[C@@](C[C@H]1O)([H])C/C(C2)=C/CCCC(O)=O

Molecular Formula

C22H32O4

Molecular Weight

360.49

Precautions

P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501

References & Citations

[1]Rücker W, et al. Evidence for high affinity prostacyclin binding sites in vascular tissue: radioligand studies with a chemically stable analogue. Biochem Pharmacol. 1983 Aug 15;32 (16) :2405-10.|[2]Sharma A, et al. Role of Vasodilator Testing in Pulmonary Hypertension. Prog Cardiovasc Dis. 2016 Jan-Feb;58 (4) :425-33.