Balofloxacin

Balofloxacin (Q-35) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin can be used for the research of respiratory, intestinal, and urinary tract infections[1][2].

Product Specifications

CAS Number

[127294-70-6]

Product Name Alternative

Q-35

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/balofloxacin.html

Purity

98.26

Solubility

DMSO : 0.67 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4CC(NC)CCC4)=C3OC)C1=O)O

Molecular Formula

C20H24FN3O4

Molecular Weight

389.42

Precautions

H302, H315, H319, H335

References & Citations

[1]Alksne L. Balofloxacin Choongwae. Curr Opin Investig Drugs. 2003 Feb;4 (2) :224-9.|[2]Jiang H, et, al. In vitro and in vivo effectiveness evaluation of balofloxacin in experimental Staphylococcus aureus keratitis. J Ocul Pharmacol Ther. 2014 Aug;30 (6) :482-8.|[3]Gohara Y, et, al. In vitro and in vivo activities of Q-35, a new fluoroquinolone, against Mycoplasma pneumonia. Antimicrob Agents Chemother. 1993 Sep;37 (9) :1826-30.