Lycorine
Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15.24 nM. Lycorine downregulates the SCAP protein level without changing its transcription[2]. Lycorine is also a melanoma vasculogenic inhibitor[3]. Lycorine can be used for the study of prostate cancer and metabolic diseases[2].
Product Specifications
CAS Number
476-28-8
UNSPSC
12352005
Hazard Statement
H301
Target
Apoptosis; Bacterial; Fatty Acid Synthase (FASN) ; Virus Protease
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Metabolic Enzyme/Protease
Applications
Neuroscience-Neurodegeneration
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lycorine.html
Concentration
10mM
Purity
99.98
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@@H](O)C=C(CC2)[C@@]3([H])N2CC4=C([C@@]31[H])C=C(OCO5)C5=C4
Molecular Formula
C16H17NO4
Molecular Weight
287.31
Precautions
H301
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Citation 01
Available Sizes
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