MTX-211
MTX-211 (Mol 211) is a dual inhibitor of EGFR and PI3K with IC50 values of [1].
Product Specifications
CAS Number
[1952236-05-3]
Product Name Alternative
Mol 211
UNSPSC
12352005
Hazard Statement
H315, H319
Target
EGFR; PI3K
Type
Reference compound
Related Pathways
JAK/STAT Signaling; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/MTX-211.html
Concentration
10mM
Purity
99.81
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CS(NC1=CC(C2=CC(C(NC3=CC(Cl)=C(F)C=C3)=NC=N4)=C4C=C2)=CN=C1Cl)(=O)=O
Molecular Formula
C20H14Cl2FN5O2S
Molecular Weight
478.33
Precautions
H315, H319
References & Citations
[1]Small molecule inhibitors of egfr and pi3k. WO 2016100347 A2
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EGFR/ErbB1/HER1; PI3K
Available Sizes
Curated Selection
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