2',3'-cGAMP (sodium)
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP sodium binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ) . 2',3'-cGAMP sodium is produced in mammalian cells in response to DNA in the cytoplasm[1].
Product Specifications
CAS Number
2734858-36-5
Product Name Alternative
2'-3'-cyclic GMP-AMP (sodium)
UNSPSC
12352005
Target
Endogenous Metabolite; IFNAR; STING
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/2-3-cgamp-sodium.html
Purity
99.89
Solubility
DMSO : < 1 mg/mL|H2O : 50 mg/mL (ultrasonic)
Smiles
OC1([H])[C@](OP(OC[C@](O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@@H]4O)([H])[C@@]4([H])O5)(O[Na])=O)([H])[C@H](N6C(NC(N)=NC7=O)=C7N=C6)O[C@]1([H])COP5(O[Na])=O
Molecular Formula
C20H22N10Na2O13P2
Molecular Weight
718.37
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Citation 01
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Ubiquitin (Autophagy Marker) (UBB/1748), CF594 conjugate, 0.1mg/mL
C10orf62 (NM_001009997) Human Over-expression Lysate
Anti-Mouse CD317 (927) In Vivo Antibody - Low Endotoxin
