2',3'-cGAMP (sodium)
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP sodium binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ) . 2',3'-cGAMP sodium is produced in mammalian cells in response to DNA in the cytoplasm[1].
Product Specifications
CAS Number
[2734858-36-5]
Product Name Alternative
2'-3'-cyclic GMP-AMP (sodium)
UNSPSC
12352005
Target
Endogenous Metabolite; IFNAR; STING
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/2-3-cgamp-sodium.html
Purity
99.89
Solubility
DMSO : < 1 mg/mL|H2O : 50 mg/mL (ultrasonic)
Smiles
OC1([H])[C@](OP(OC[C@](O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@@H]4O)([H])[C@@]4([H])O5)(O[Na])=O)([H])[C@H](N6C(NC(N)=NC7=O)=C7N=C6)O[C@]1([H])COP5(O[Na])=O
Molecular Formula
C20H22N10Na2O13P2
Molecular Weight
718.37
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Citation 01
Available Sizes
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