ISX-3
Product Specifications
UNSPSC Description
ISX-3 is a potent anti-adipogenic and pro-osteogenic agent. ISX-3 increases the expression of PPARγ. ISX-3 has the potential for the research of osteopenia and osteoporosis[1].
Target Antigen
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/isx-3.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=NOC(C2=CC(Cl)=CC=C2)=C1)NCCCN3C=NC=C3
Molecular Weight
330.77
References & Citations
[1]Nawa K, et al. Discovering small molecules that inhibit adipogenesis and promote osteoblastogenesis: unique screening and Oncostatin M-like activity. Differentiation. 2013 Jul-Sep;86(1-2):65-74.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148694/ISX-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148694/ISX-3-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
912789-08-3
Available Sizes
Curated Selection
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