Hydroxytanshinone IIA
Hydroxytanshinone IIA is a hydroxylated metabolite of Tanshinone IIA. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2[1].
Product Specifications
CAS Number
[18887-18-8]
UNSPSC
12352005
Target
Drug Metabolite; VEGFR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hydroxytanshinone-iia.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C2C=CC3=C1C(O)CCC3(C)C)C(C4=C2OC=C4C)=O
Molecular Formula
C19H18O4
Molecular Weight
310.34
References & Citations
[1]Peng Li, et al. Simultaneous determination of tanshinone IIA and its three hydroxylated metabolites by liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom. 2006;20 (5) :815-22.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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