NVS-VHL720
NVS-VHL720 is a molecular glue degrader that targets cysteine dioxygenase (CDO1) [1].
Product Specifications
UNSPSC
12352005
Target
Molecular Glues
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdo1-degrader-1.html
Purity
98.63
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NCC1=CC=C(C2=CC=NN2)C3=C1C=CC=C3)[C@H]4N(C([C@@H](NC(C)=O)C(C)(C)C)=O)C[C@H](O)C4
Molecular Formula
C27H33N5O4
Molecular Weight
491.58
References & Citations
[1]Tutter A, et al. A small molecule VHL molecular glue degrader for cysteine dioxygenase 1[J]. bioRxiv, 2024: 2024.01. 25.576086.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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