NVS-VHL720

NVS-VHL720 is a molecular glue degrader that targets cysteine dioxygenase (CDO1) [1].

Product Specifications

UNSPSC

12352005

Target

Molecular Glues

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cdo1-degrader-1.html

Purity

98.63

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NCC1=CC=C(C2=CC=NN2)C3=C1C=CC=C3)[C@H]4N(C([C@@H](NC(C)=O)C(C)(C)C)=O)C[C@H](O)C4

Molecular Formula

C27H33N5O4

Molecular Weight

491.58

References & Citations

[1]Tutter A, et al. A small molecule VHL molecular glue degrader for cysteine dioxygenase 1[J]. bioRxiv, 2024: 2024.01. 25.576086.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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