Kuromanin (chloride)

Kuromanin chloride (Chrysontemin) is derived from mulberry leaves and has the effect of increasing blood sugar concentration and maintaining lipid metabolism balance to reduce obesity. Kuromanin chloride can inhibit CD38 enzymatic activities[1][2][3].

Product Specifications

CAS Number

[7084-24-4]

Product Name Alternative

Chrysontemin; Cyanidin 3-O-glucoside chloride

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

CD38

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Kuromanin-chloride.html

Purity

99.83

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O[C@H]([C@@H](O)[C@@H]1O)[C@@H](O[C@@H]1CO)OC(C(C2=CC(O)=C(O)C=C2)=[O+]C3=CC(O)=C4)=CC3=C4O.[Cl-]

Molecular Formula

C21H21ClO11

Molecular Weight

484.84

Precautions

H302, H315, H319, H335

References & Citations

[1]Ha -Na Na, et al. Reduction of adenovirus 36-induced obesity andin?ammation by mulberry extract. Microbiol Immunol 2014; 58: 303–306|[2]Winter AN, et al. Chemical basis for the disparate neuroprotective effects of the anthocyanins, callistephin and kuromanin, against nitrosative stress. Free Radic Biol Med. 2017 Feb;103:23-34.|[3]Vaisitti T, et al. The enzymatic activities of CD38 enhance CLL growth and trafficking: implications for therapeutic targeting. Leukemia. 2015 Feb;29 (2) :356-68.