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Tolamolol

Tolamolol is a selective beta-adrenergic antagonist with significant activity in reducing exercise-induced ST-segment depression. Tolamolol is clinically equivalent to propranolol in suppressing angina and exhibits greater cardiac selectivity. Tolamolol is effective in reducing the frequency of angina attacks and the amount of glyceryl trinitrate used. Tolamolol is effective in lowering blood pressure and has a positive effect on increasing the amount of exercise that can be performed before angina attacks. The use of Tolamolol also helps improve the suppression of arrhythmias[1].

Product Specifications

CAS Number

38103-61-6

UNSPSC

12352005

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/tolamolol.html

Smiles

O=C(C1=CC=C(C=C1)OCCNCC(COC2=C(C)C=CC=C2)O)N

Molecular Formula

C19H24N2O4

Molecular Weight

344.40

References & Citations

[1]Double-blind comparison of tolamolol, propranolol, practolol, and placebo in the treatment of angina pectoris

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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