Tolamolol
Tolamolol is a selective beta-adrenergic antagonist with significant activity in reducing exercise-induced ST-segment depression. Tolamolol is clinically equivalent to propranolol in suppressing angina and exhibits greater cardiac selectivity. Tolamolol is effective in reducing the frequency of angina attacks and the amount of glyceryl trinitrate used. Tolamolol is effective in lowering blood pressure and has a positive effect on increasing the amount of exercise that can be performed before angina attacks. The use of Tolamolol also helps improve the suppression of arrhythmias[1].
Product Specifications
CAS Number
38103-61-6
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/tolamolol.html
Smiles
O=C(C1=CC=C(C=C1)OCCNCC(COC2=C(C)C=CC=C2)O)N
Molecular Formula
C19H24N2O4
Molecular Weight
344.40
References & Citations
[1]Double-blind comparison of tolamolol, propranolol, practolol, and placebo in the treatment of angina pectoris
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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