SWE101
Product Specifications
UNSPSC Description
SWE101 (compound 22 b) is a potent soluble epoxide hydrolase (sEH)-P inhibitor with IC50s of 4 μM and 2.8 μM for human and rat sEH-P, respectively. SWE101 does not inhibit neither hydrolase nor phosphatase activity of the mouse sEH[1].
Target Antigen
Epoxide Hydrolase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/swe101.html
Purity
99.41
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)CCCC1=NC(C2=CC=C(Cl)C(Cl)=C2)=C(C3=CC=CC=C3)O1
Molecular Weight
376.23
References & Citations
[1]Kramer JS, et al. Discovery of first in vivo active inhibitors of soluble epoxide hydrolase (sEH) phosphatase domain. J Med Chem. 2019 Aug 22.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-126326/SWE101-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-126326/SWE101-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2376322-12-0
Available Sizes
Curated Selection
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