C[Arg-Arg-Arg-Arg-Nal-Nal-Nal]
C[Arg-Arg-Arg-Arg-Nal-Nal-Nal] (Compound 9C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 25 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively[1].
Product Specifications
CAS Number
2619854-01-0
UNSPSC
12352209
Target
Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/c-arg-arg-arg-arg-nal-nal-nal.html
Solubility
H2O
Smiles
O=C(N[C@H](C(N[C@@H](C(N[C@@H](C1=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CC2=CC(C=CC=C3)=C3C=C2)[C@@H](NC([C@@H](NC([C@H](NC([C@H](N1)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CC4=CC(C=CC=C5)=C5C=C4)=O)CC6=CC(C=CC=C7)=C7C=C6
Molecular Formula
C63H81N19O7
Molecular Weight
1216.44
References & Citations
[1]Sandeep Lohan, et al. Small Amphiphilic Peptides: Activity Against a Broad Range of Drug-Resistant Bacteria and Structural Insight into Membranolytic Properties. J Med Chem. 2022 Jan 13;65 (1) :665-687.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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