DSM-421
DSM-421 is an orally active Dihydroorotate dehydrogenase inhibitor. DSM-421 has antiplasmodium activity[1].
Product Specifications
CAS Number
2011769-21-2
UNSPSC
12352005
Target
Dihydroorotate Dehydrogenase; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dsm-421.html
Solubility
10 mM in DMSO
Smiles
FC(F)(C1=NC=C(NC2=CC(C)=NC3=NC(C(F)(C)F)=NN32)C=C1)F
Molecular Formula
C14H11F5N6
Molecular Weight
358.27
References & Citations
[1]Phillips MA, et al. A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria. ACS Infect Dis. 2016 Dec 9;2 (12) :945-957.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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