(R) -INCB054329
(R) -INCB054329 is the isomer of INCB054329 (HY-112504), and can be used as an experimental control. INCB054329 is a potent BET inhibitor.
Product Specifications
CAS Number
[1628607-63-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-incb054329.html
Purity
98.94
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1NC2=C3N1[C@H](C4=NC=CC=C4)COC3=C(C5=C(C)ON=C5C)C=C2
Molecular Formula
C19H16N4O3
Molecular Weight
348.36
Precautions
H302, H315, H319, H335
References & Citations
[1]Pérez-Salvia M, et al. Bromodomain inhibitors and cancer therapy: From structures to applications. Epigenetics. 2017 May 4;12 (5) :323-339.|[2]Phillip CC Liu, et al. Abstract 3523: Discovery of a novel BET inhibitor INCB054329.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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