(R) -INCB054329

(R) -INCB054329 is the isomer of INCB054329 (HY-112504), and can be used as an experimental control. INCB054329 is a potent BET inhibitor.

Product Specifications

CAS Number

[1628607-63-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/r-incb054329.html

Purity

98.94

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1NC2=C3N1[C@H](C4=NC=CC=C4)COC3=C(C5=C(C)ON=C5C)C=C2

Molecular Formula

C19H16N4O3

Molecular Weight

348.36

Precautions

H302, H315, H319, H335

References & Citations

[1]Pérez-Salvia M, et al. Bromodomain inhibitors and cancer therapy: From structures to applications. Epigenetics. 2017 May 4;12 (5) :323-339.|[2]Phillip CC Liu, et al. Abstract 3523: Discovery of a novel BET inhibitor INCB054329.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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