Purified Anti-Human CD276 Antibody[6A1]
Product Specifications
Background
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Abbreviation
CD276
Gene ID
80381
UniProt
Q5ZPR3
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD276 protein
Target
B7H; UNQ; PRO; B7-H; B7RP; B7 homolog; B7H34Ig-B7-H; PSEC;4Ig-B7-H; CD276;4Ig-B7-H3; B7-H3; B7H3; B7RP-2; B7 homolog 3; B7H34Ig-B7-H3; CD276 antigen; CD276 molecule; Costimulatory molecule; PSEC0249; UNQ309; PRO352; B7RP-2;4Ig-B7-H3; B7H3; B7-H3; CD276 antigen
Clonality
Monoclonal
Clone
6A1
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology; Cancer; Stem Cells
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/w5xdv5
Product MSDS
https://789.bio/eb/WDlqaL
Isotype
Mouse IgG1, κ
Available Sizes
Curated Selection
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