Cedazuridine
Product Specifications
UNSPSC Description
Cedazuridine (E7727) (Compound 7a) is an orally active cytidine deaminase (CDA) inhibitor with an IC50 value of 0.4 μM. Cedazuridine can be used for cancer research[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cedazuridine.html
Purity
98.0
Solubility
DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O[C@H]1C(F)(F)[C@H](N(CC[C@@H](O)N2)C2=O)O[C@@H]1CO
Molecular Weight
268.21
References & Citations
[1]Ferraris D, et al. Design, synthesis, and pharmacological evaluation of fluorinated tetrahydrouridine derivatives as inhibitors of cytidine deaminase. J Med Chem. 2014 Mar 27; 57(6):2582-8.|[2]Ramsey H E, et al. Oral azacitidine and cedazuridine approximate parenteral azacitidine efficacy in murine model. Targeted Oncology, 2020, 15(2): 231-240.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-109081/Cedazuridine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-109081/Cedazuridine-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
1141397-80-9
Available Sizes
Curated Selection
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