VBIT-4
Product Specifications
UNSPSC Description
VBIT-4 is an inhibitor of voltage-dependent anion channel 1 (VDAC1) oligomerization with a binding affinity (Kd) of 17 μM. VBIT-4, as an apoptosis inhibitor, can be used for therapeutic purposes in apoptosis-associated disorders, such as neurodegenerative and cardiovascular diseases[1].
Target Antigen
VDAC
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/vbit-4.html
Purity
99.46
Solubility
DMSO : 125 mg/mL (ultrasonic)|H2O : 1 mg/mL (ultrasonic;adjust pH to 3 with HCl)
Smiles
O=C(NC1=CC=C(Cl)C=C1)CC(CO)N2CCN(C3=CC=C(OC(F)(F)F)C=C3)CC2
Molecular Weight
457.87
References & Citations
[1]Ben-Hail D, et al. Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction. J Biol Chem. 2016 Nov 25;291(48):24986-25003.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-129122/VBIT-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-129122/VBIT-4-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2086257-77-2
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Elab Fluor® Red 780 Anti-Mouse CD49b/pan-NK cells Antibody[DX5]](https://cdn.genprice.uk/genprice/genprice2.png)
E-AB-F1116US-01 25 µg
Elab Fluor® Red 780 Anti-Mouse CD49b/pan-NK cells Antibody[DX5]
Ask
View Details E-AB-F1116US-02 100 µg
Elab Fluor® Red 780 Anti-Mouse CD49b/pan-NK cells Antibody[DX5]
Ask
View Details 
