Artepillin C (Standard)
Artepillin C (Standard) is the analytical standard of Artepillin C. This product is intended for research and analytical applications. Artepillin C is an orally active CREB/CRTC2 inhibitor and TRPA1 covalent agonist (EC50=1.8 μM). Artepillin C inhibits CREB/CRTC2-mediated gene transcription and downregulates BMAL1 expression to regulate glucose and lipid metabolism. Artepillin C can also activate TRPA1 channels to induce spicy taste signals. Artepillin C can inhibit tumor cell proliferation, induce apoptosis, improve insulin resistance and inhibit liver lipid synthesis. Artepillin C can be used in the study of metabolic syndrome, tumor prevention and treatment, and inflammation[1][2][3][4].
Product Specifications
CAS Number
72944-19-5
UNSPSC
12352005
Target
Epigenetic Reader Domain; Necroptosis; Reference Standards; TRP Channel
Type
Reference Standards
Related Pathways
Apoptosis; Epigenetics; Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/artepillin-c-standard.html
Smiles
C/C(C)=C\CC1=C(C(C/C=C(C)\C)=CC(/C=C/C(O)=O)=C1)O
Molecular Formula
C19H24O3
Molecular Weight
300.39
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Isoform
TRPA1
Frequently Asked Questions
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