MS-L6
MS-L6 is a potent inhibitor of oxidative phosphorylation (OXPHOS) that can acts as electron transport chain complexes I (ETC-I) combining inhibition of NADH oxidation and uncoupling effect[1].
Product Specifications
CAS Number
[63498-32-8]
UNSPSC
12352005
Target
Mitochondrial Metabolism; Oxidative Phosphorylation
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ms-l6.html
Purity
99.95
Solubility
DMSO : 125 mg/mL (ultrasonic) |H2O : 4 mg/mL (ultrasonic)
Smiles
N=C(NC1=CC=CC=C1)SCCCCCCSC(NC2=CC=CC=C2)=N.Br.Br
Molecular Formula
C20H28Br2N4S2
Molecular Weight
548.40
References & Citations
[1]Alaa Al Assi, et al. A novel inhibitor of the mitochondrial respiratory complex I with uncoupling properties exerts potent antitumor activity. Cell Death Dis. 2024 May 2;15 (5) :311.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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