MS-L6

MS-L6 is a potent inhibitor of oxidative phosphorylation (OXPHOS) that can acts as electron transport chain complexes I (ETC-I) combining inhibition of NADH oxidation and uncoupling effect[1].

Product Specifications

CAS Number

[63498-32-8]

UNSPSC

12352005

Target

Mitochondrial Metabolism; Oxidative Phosphorylation

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ms-l6.html

Purity

99.95

Solubility

DMSO : 125 mg/mL (ultrasonic) |H2O : 4 mg/mL (ultrasonic)

Smiles

N=C(NC1=CC=CC=C1)SCCCCCCSC(NC2=CC=CC=C2)=N.Br.Br

Molecular Formula

C20H28Br2N4S2

Molecular Weight

548.40

References & Citations

[1]Alaa Al Assi, et al. A novel inhibitor of the mitochondrial respiratory complex I with uncoupling properties exerts potent antitumor activity. Cell Death Dis. 2024 May 2;15 (5) :311.