Protirelin (acetate)

Protirelin Acetate is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions.

Product Specifications

CAS Number

[120876-23-5]

Product Name Alternative

Thyrotropin-releasing-hormone (acetate) ; TRH (acetate)

UNSPSC

12352209

Target

Thyroid Hormone Receptor

Type

Peptides

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Endocrinology; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Protirelin-Acetate.html

Purity

99.98

Solubility

DMSO : 233.33 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(N)[C@H]1N(C([C@H](CC2=CNC=N2)NC([C@H](CC3)NC3=O)=O)=O)CCC1.[1.5CH3COOH]

Molecular Formula

C16H22N6O4.3/2C2H4O2

Molecular Weight

452.46

References & Citations

[1]Van Sinay E, et al. Evolutionarily conserved TRH neuropeptide pathway regulates growth in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2017 May 16;114 (20) :E4065-E4074.|[2]Noda Y, et al. Hyperthermia induced by thyrotropin-releasing hormone (TRH, Protirelin) in the rat. Kurume Med J. 1979;26 (2) :107-12.