FA-Phe-Phe
FA-Phe-Phe is a furylacryloyl (fa) -amino acid derivative, targeting to Angiotensin-converting Enzyme (ACE) . FA-Phe-Phe is also a specific substrate of Cathepsin A[1][2].
Product Specifications
CAS Number
83661-95-4
UNSPSC
12352209
Target
Angiotensin-converting Enzyme (ACE)
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/fa-phe-phe.html
Solubility
10 mM in DMSO
Smiles
OC([C@H](CC1=CC=CC=C1)NC([C@@H](NC(/C=C/C2=CC=CO2)=O)CC3=CC=CC=C3)=O)=O
Molecular Formula
C25H24N2O5
Molecular Weight
432.47
References & Citations
[1]Mayer M, et al. Mapping the active site of angiotensin-converting enzyme by transferred NOE spectroscopy. J Med Chem. 2000 Jun 1;43 (11) :2093-9.|[2]Ostrowska H, et al. Lactacystin, a specific inhibitor of the proteasome, inhibits human platelet lysosomal cathepsin A-like enzyme. Biochem Biophys Res Commun. 1997 May 29;234 (3) :729-32.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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